Infection with Zika virus is an emerging public health crisis. We observed prolonged detection of virus RNA in vaginal mucosal swab specimens and whole blood for a US traveler with acute Zika virus infection who had visited Honduras. These findings advance understanding of Zika virus infection and provide data for additional testing strategies.
Keywords: Honduras; PCR; United States; Zika virus; erythrocytes; infection; natural history; prolonged detection; saliva; traveler; urine; vaginal secretions; virus isolation; virus shedding; viruses; whole blood.