Local Anesthetics Systemic Toxicity

J Assoc Physicians India. 2016 Mar;64(3):92-93.

Abstract

Lidocaine Hydrochloride is an amide ester, which is widely used local anesthetic agent that is well tolerated but what is less known is the occurrence of systemic toxicity which manifests in the central nervous and cardiovascular systems. We report here 3 cases of Lidocaine associated Seizures.

Publication types

  • Case Reports

MeSH terms

  • Administration, Intravenous
  • Adult
  • Anesthetics, Local / administration & dosage
  • Anesthetics, Local / adverse effects*
  • Diazepam / administration & dosage
  • Diazepam / therapeutic use
  • Female
  • Humans
  • Lidocaine / administration & dosage
  • Lidocaine / adverse effects*
  • Male
  • Middle Aged
  • Seizures / chemically induced*
  • Seizures / drug therapy
  • Treatment Outcome

Substances

  • Anesthetics, Local
  • Lidocaine
  • Diazepam