Targeting p21 activated kinase 1 (Pak1) to PAKup Pancreatic Cancer

Expert Opin Ther Targets. 2016 Nov;20(11):1283-1285. doi: 10.1080/14728222.2016.1239719. Epub 2016 Sep 30.

Authors

Sankar Jagadeeshan^{1

2}, Ganesh Venkatraman³, Suresh K Rayala¹

Affiliations

¹ a Department of Biotechnology , IIT Madras , Chennai , India.
² b Department of Genetics , University of Madras , Chennai , India.
³ c Department of Human Genetics , Sri Ramachandra University , Chennai , India.

PMID: 27654702
DOI: 10.1080/14728222.2016.1239719

No abstract available

Keywords: Pak1; Pak1 inhibitors; gemcitabine resistance; pancreatic adenocarcinoma.

MeSH terms

Antineoplastic Agents / pharmacology*
Gene Expression Regulation / drug effects*
Humans
Molecular Targeted Therapy
Pancreatic Neoplasms / drug therapy*
p21-Activated Kinases / metabolism*

Substances

Antineoplastic Agents
PAK1 protein, human
p21-Activated Kinases