Synthesis of nanosilver loaded chitosan/poly(acrylamide-co-itaconic acid) based inter-polyelectrolyte complex films for antimicrobial applications

Carbohydr Polym. 2016 Dec 10:154:223-30. doi: 10.1016/j.carbpol.2016.08.044. Epub 2016 Aug 16.

Abstract

In the present work, AgNPs loaded chitosan/poly(acrylamide-co-itaconic acid) inter-polyelectrolyte complex (IPC) films have been prepared for antimicrobial applications. The AgNPs-loaded IPC films have been characterized by Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), Transmission electron microscopy (TEM), Scanning electron microscopy (SEM), Thermogravimetric analysis (TGA) and Surface plasmon resonance (SPR). Particle size of synthesized AgNPs was found to be in the range 10-30nm. These films exhibited a remarkable antibacterial property against strong pathogen E.Coli, thus offering their candidature for antimicrobial applications.

Keywords: AgNPs; Antibacterial property; IPC films; Wound dressing.

MeSH terms

  • Acrylic Resins / chemistry
  • Anti-Infective Agents / chemical synthesis
  • Anti-Infective Agents / chemistry*
  • Chitosan / chemistry
  • Escherichia coli / drug effects
  • Metal Nanoparticles / chemistry*
  • Microscopy, Electron, Scanning
  • Microscopy, Electron, Transmission
  • Particle Size
  • Polyelectrolytes / chemistry*
  • Silver / chemistry*
  • Spectroscopy, Fourier Transform Infrared
  • Succinates / chemistry
  • Surface Plasmon Resonance
  • Thermogravimetry
  • X-Ray Diffraction

Substances

  • Acrylic Resins
  • Anti-Infective Agents
  • Polyelectrolytes
  • Succinates
  • Silver
  • polyacrylamide
  • Chitosan
  • itaconic acid