Miscarriage following dengue virus 3 infection in the first six weeks of pregnancy of a dengue virus-naive traveller returning from Bali to Italy, April 2016

Euro Surveill. 2016 Aug 4;21(31):30308. doi: 10.2807/1560-7917.ES.2016.21.31.30308.

Abstract

We report miscarriage following dengue virus (DENV)-3 infection in a pregnant woman returning from Bali to Italy in April 2016. On her arrival, the woman had fever, rash, asthenia and headache. DENV RNA was detected in plasma and urine samples collected the following day. Six days after symptom onset, she had a miscarriage. DENV RNA was detected in fetal material, but in utero fetal infection cannot be demonstrated due to possible contamination by maternal blood.

Keywords: dengue virus 3; pregnancy; travel.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Spontaneous / virology*
  • Antibodies, Viral / blood*
  • Asthenia / virology
  • Dengue / blood
  • Dengue / complications
  • Dengue / diagnosis*
  • Dengue / virology
  • Dengue Virus / classification
  • Dengue Virus / genetics
  • Dengue Virus / immunology
  • Dengue Virus / isolation & purification*
  • Enzyme-Linked Immunosorbent Assay
  • Exanthema / virology
  • Female
  • Fever / etiology
  • Fever / virology
  • Headache / virology
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin G / immunology
  • Immunoglobulin M / blood
  • Immunoglobulin M / immunology
  • Indonesia
  • Infectious Disease Transmission, Vertical
  • Italy
  • Pregnancy
  • Pregnancy Complications, Infectious / virology*
  • Pregnancy Outcome
  • Pregnancy Trimester, First
  • RNA, Viral / genetics*
  • Sequence Analysis, DNA
  • Travel

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Immunoglobulin M
  • RNA, Viral