Display Settings:

Format

Send to:

Choose Destination
Genomics. 1989 May;4(4):552-9.

Human monoamine oxidase A and B genes map to Xp 11.23 and are deleted in a patient with Norrie disease.

Author information

  • 1Division of Biological Sciences, School of Pharmacy, University of Southern California, Los Angeles 90033.

Abstract

Monoamine oxidase A and B (MAO A and B) are the central enzymes that catalyze oxidative deamination of biogenic amines throughout the body. The regional locations of genes encoding MAO A and B on the X chromosome were determined by using full-length cDNA clones for human MAO A and B, respectively. Using somatic cell hybrids, in situ hybridization, and field-inversion gel electrophoresis as well as deletion mapping in a patient with Norrie disease, we concluded that these two genes are close to each other and to the DXS7 locus (Xp 11.3).

PMID:
2744764
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk