Broadening the detection view of 2D photoacoustic tomography using two linear array transducers

Opt Express. 2016 Jun 13;24(12):12755-68. doi: 10.1364/OE.24.012755.

Abstract

Although commercial linear array transducers are widely used in clinical ultrasound, their application in photoacoustic tomography (PAT) is still limited due to the limited-view problem that restricts the image quality. In this paper, we propose a simple approach to address the limited-view problem in 2D by using two linear array transducers to receive PAT signal from different orientations. The positions of the two transducers can be adjusted to fit the specific geometry of an imaging site. This approach is made possible by using a new calibration method, where the relative position between the two transducers can be calibrated using ultrasound by transmitting ultrasound wave with one transducer while receiving with the other. The calibration results are then applied in the subsequent PAT imaging to incorporate the detected acoustic signals from both transducers and thereby increase the detection view. In this calibration method, no calibration phantom is required which largely simplifies and shortens the process. The efficacy of the calibration and improvement on the PAT image quality are demonstrated through phantom studies and in vivo imaging.