McArdle's disease--what limit to the age of onset?

S Afr Med J. 1978 Jan 14;53(2):60-3.

Abstract

A patient with McArdle's disease is reported in whome proximal muscle weakness began in the 7th decade. Other unusual features included the absence of muscle cramps at any stage, asymmetrical wasting of the shoulder girdle muscles and calf hypertrophy. Muscle biopsy revealed a vacuolar myopathy, absent phosphorylase staining and qualitatively low glycogen content.

Publication types

  • Case Reports

MeSH terms

  • Age Factors
  • Aged
  • Glycogen Storage Disease / pathology*
  • Glycogen Storage Disease Type V / enzymology
  • Glycogen Storage Disease Type V / pathology*
  • Humans
  • Male
  • Muscles / enzymology
  • Muscles / pathology
  • Muscles / ultrastructure
  • Phosphorylases / deficiency

Substances

  • Phosphorylases