The cerebral vasculature in dementia pugilistica

J Neurol Neurosurg Psychiatry. 1989 May;52(5):600-4. doi: 10.1136/jnnp.52.5.600.

Abstract

The brains of 22 ex-boxers were examined histologically to determine the frequency of recent or old haemorrhage. Four boxers had died from an acute intracerebral bleed, usually soon after a boxing bout. Seven of the other 18 showed evidence of previous perivascular haemorrhage, as detected by Perls' ferrocyanide test for iron, and a similar number showed minor degrees of meningeal or subpial siderosis, consistent with previous meningeal bleeding; cerebellar siderosis was present in six cases. Seventeen of the 22 boxers showed evidence of recent or past haemorrhage. Control material showed an incidence of 11% for perivascular iron deposition and only 4% for minor degrees of meningeal siderosis.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Athletic Injuries / complications
  • Athletic Injuries / pathology*
  • Boxing*
  • Brain Injuries / complications
  • Brain Injuries / pathology*
  • Cerebral Hemorrhage / pathology*
  • Cumulative Trauma Disorders / pathology*
  • Dementia / etiology
  • Dementia / pathology*
  • Female
  • Humans
  • Male
  • Middle Aged