Trend of invasive pneumococal disease (IPD) in a South Western, Nigerian hospital

Pan Afr Med J. 2016 Mar 28:23:140. doi: 10.11604/pamj.2016.23.140.5635. eCollection 2016.

Abstract

The recent introduction of the Heptavalent-pneumococcal vaccine (PCV-7) by private pharmaceutical companies in Nigeria, has generated interest in invasive bacterial diseases particularly IPD. Our objective in this study is to investigate the trend and occurrence rate of IPD in Abeokuta, Nigeria. Suspected IPD cases were assessed from Jan 2010 to Dec 2010 for demographic and Microbiological characteristics. Bacterial isolations and antibiotics susceptibility testing followed standard bacteriological procedure. Overall 471 cases of probable IPD was assessed, with 21(4.5%) cases of suspected pneumonia, 109(23.1%) cases of suspected meningitis, and 341(72.4%) cases of suspected septicaemia. Confirmed IPD cases were 9 with 2 cases of meningitis, 3 cases of septicaemia and 4 cases of pneumonia. Age range distribution showed, high distribution of IPD cases among children >1 with 5(55.6%) there was a statistically significant difference in gender p< 0.05 (X2 test) with females recording a higher occurrence than males. We conclude by advocating for better detection methods against IPD meningitis cases, and continuous surveillance into the serotypes of streptococcus pneumonia as well inclusion of the PCV vaccine into our childhood immunization program.

Keywords: Abeokuta; IPD; Immunization; streptococcus pneumonia.

MeSH terms

  • Adolescent
  • Age Distribution
  • Anti-Bacterial Agents / pharmacology
  • Child
  • Child, Preschool
  • Female
  • Heptavalent Pneumococcal Conjugate Vaccine / administration & dosage
  • Humans
  • Infant
  • Male
  • Meningitis, Pneumococcal / epidemiology*
  • Meningitis, Pneumococcal / microbiology
  • Microbial Sensitivity Tests
  • Nigeria / epidemiology
  • Pneumococcal Infections / epidemiology*
  • Pneumonia, Pneumococcal / epidemiology*
  • Pneumonia, Pneumococcal / microbiology
  • Sepsis / epidemiology*
  • Sepsis / microbiology
  • Sex Distribution
  • Streptococcus pneumoniae / drug effects
  • Streptococcus pneumoniae / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Heptavalent Pneumococcal Conjugate Vaccine