Induction, labor length and mode of delivery: the impact on preeclampsia-related adverse maternal outcomes

J Perinatol. 2016 Sep;36(9):713-7. doi: 10.1038/jp.2016.84. Epub 2016 May 19.

Abstract

Objective: The objectives were to evaluate whether induction, specifically prolonged labor, was associated with adverse maternal outcomes related to preeclampsia with severe features (PEC-S) and whether cesarean affected the rate.

Study design: This was a retrospective cohort study of women with PEC-S ⩾34 weeks who were diagnosed either before planned cesarean or before induction/latent labor. The primary outcome was a composite adverse maternal outcome related to PEC-S.

Results: The final cohort comprised 193 women (n=172 with labor and n=21 with planned cesarean). The prevalence of the outcome was 15.5%. Women exposed to labor did not have a higher rate compared with planned cesarean (16.3% vs 9.5%, P=0.4). Adjusting for confounders, women with a cesarean after prolonged labor had a 10-fold higher adverse outcome risk compared with women with a planned cesarean (adjusted odds ratio (aOR) 9.7 (1.2 to 78.6), P=0.03) or with a vaginal delivery <24 h (aOR 9.7 (1.4 to 67.4), P=0.02).

Conclusion: Prolonged labor and cesarean in labor were both associated with an increase in our outcome.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Cesarean Section / statistics & numerical data*
  • Female
  • Humans
  • Labor, Induced / statistics & numerical data*
  • Logistic Models
  • Odds Ratio
  • Pennsylvania
  • Pre-Eclampsia / epidemiology*
  • Pregnancy
  • Pregnancy Outcome
  • Retrospective Studies
  • Young Adult