A New Genomics-Driven Taxonomy of Bacteria and Archaea: Are We There Yet?

J Clin Microbiol. 2016 Aug;54(8):1956-63. doi: 10.1128/JCM.00200-16. Epub 2016 May 18.

Abstract

Taxonomy is often criticized for being too conservative and too slow and having limited relevance because it has not taken into consideration the latest methods and findings. Yet the cumulative work product of its practitioners underpins contemporary microbiology and serves as a principal means of shaping and referencing knowledge. Using methods drawn from the field of exploratory data analysis, this minireview examines the current state of the field as it transitions from a taxonomy based on 16S rRNA gene sequences to one based on whole-genome sequences and tests the validity of some commonly held beliefs.

Publication types

  • Review
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Archaea / classification*
  • Archaea / genetics*
  • Bacteria / classification*
  • Bacteria / genetics*
  • Classification / methods*
  • Genomics / methods*
  • Humans

Grants and funding

Portions of the funding are through the SBIR/STTR program.