Insights from synthetic yeasts

Yeast. 2016 Sep;33(9):483-92. doi: 10.1002/yea.3169. Epub 2016 Jun 10.

Abstract

Synthetic biology is one of the most exciting strategies for the investigation of living organisms and lies at the intersection of biology and engineering. Originally developed in prokaryotes, the idea of deciphering biological phenomena through building artificial genetic circuits and studying their behaviours has rapidly demonstrated its potential in a broad range of fields in the life sciences. From the assembly of synthetic genomes to the generation of novel biological functions, yeast cells have imposed themselves as the most powerful eukaryotic model for this approach. However, we are only beginning to explore the possibilities of synthetic biology, and the perspectives it offers in a genetically amenable system such as yeasts are endless. Copyright © 2016 John Wiley & Sons, Ltd.

Keywords: Genetic engineering; Synthetic biology; Yeast.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Artificial Cells*
  • DNA, Fungal
  • Gene Expression Regulation, Fungal
  • Genetic Engineering
  • Yeasts / cytology*
  • Yeasts / genetics
  • Yeasts / physiology*

Substances

  • DNA, Fungal