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J Neurosci Methods. 1989 Mar;27(2):173-80.

A fractal analysis of cell images.

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  • 1Laboratory of Neurophysiology, NINDS, National Institutes of Health, Bethesda, MD 20892.

Erratum in

  • J Neurosci Methods 1990 Mar;31(3):251.


Methods of digital image analysis have been adapted to measure the fractal dimension of cellular profiles. The fractal dimension is suggested as a useful measure of the complexity of a contour. Three methods produce similar results when applied to constructed, near-ideal fractal figures. Comparison of the measurements for a variety of image types indicates the measurement accuracy in each case and may help in interpreting the results when applied to real, non-ideal cell images of unknown fractal dimension. Two of the methods are currently adopted as appropriate for use on neuronal contours. A correlation exists between the complexity of these contours and the magnitude of the estimated fractal dimension.

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