Takayasu arteritis presenting with total occlusion of the left main coronary artery ostium: an extremely rare occurrence

BMJ Case Rep. 2016 Apr 15:2016:10.1136/bcr-2016-214531. doi: 10.1136/bcr-2016-214531.

Abstract

A young 18-year-old female patient with exertional angina and claudication of the upper limbs was subjected to angiography. Bruits were auscultated over the bilateral renal arteries, right subclavian and right common carotid arteries. There was asymmetry of peripheral pulses. Laboratory parameters demonstrated a high erythrocyte sedimentation rate and C reactive protein. An aortic angiogram revealed a typical picture of Takayasu arteritis with bilateral subclavian, common carotid and renal involvement. A coronary angiogram was performed which showed total occlusion of the left main coronary artery. There was retrograde filling of the left coronary artery on right coronary artery injection up to the ostium of the left main coronary artery. Since the markers for disease activity were high, the patient was started on steroids and urgent coronary artery bypass grafting was planned. Unfortunately, the patient refused urgent intervention and was later lost to follow-up. This case describes an extremely rare occurrence of total occlusion of the left main coronary artery ostium in a patient with Takayasu arteritis.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Angina, Stable / diagnostic imaging
  • Angina, Stable / etiology
  • Aortography
  • Carotid Artery, Common / diagnostic imaging
  • Carotid Artery, Common / physiopathology
  • Coronary Angiography
  • Coronary Artery Disease / diagnostic imaging
  • Coronary Artery Disease / etiology*
  • Coronary Occlusion / diagnostic imaging
  • Coronary Occlusion / etiology*
  • Female
  • Humans
  • Intermittent Claudication / diagnostic imaging
  • Intermittent Claudication / etiology
  • Lost to Follow-Up
  • Takayasu Arteritis / complications*
  • Takayasu Arteritis / diagnostic imaging
  • Upper Extremity / blood supply
  • Upper Extremity / diagnostic imaging