Associations between inhaler technique and asthma control among asthma patients using pressurised MDIs and DPIs

Int J Tuberc Lung Dis. 2016 May;20(5):689-95. doi: 10.5588/ijtld.15.0557.

Abstract

Objectives: To investigate associations between technique with pressurised metered-dose inhalers (pMDIs) and dry powder inhalers (DPIs) used as controller medication and asthma control variables measured using Asthma Control Test (ACT) scores.

Design: In this cross-sectional study, the inhaler technique of asthma patients using pMDIs or DPIs (Turbuhaler® [TH] and Accuhaler Diskus™ [ACC]) were assessed against published inhaler technique checklists. ACT scores (maximum 25, higher score corresponding to better asthma control) were assessed.

Results: Of the 130 subjects enrolled in the study (41 TH, 54 ACC and 35 pMDI), inhaler technique scores (out of nine for all devices) were low for TH (4.4 ± 0.9) and ACC (5.4 ± 1.0) compared with pMDI (8.1 ± 0.9) (P < 0.001, one-way analysis of variance). Older age and use of pMDI were associated with better inhaler technique. ACT scores were low, consistent with very poorly controlled asthma (mean TH 13.1 ± SD 3.9, mean ACC 13.3 ± SD 3.9 and mean pMDI 12.8 ± SD 4.2). No significant association between inhaler technique scores and ACT scores was found. More recent asthma diagnosis and a higher level of education were associated with higher ACT scores (better asthma control).

Conclusion: Asthma control was poor in this population. Lack of a significant association between the inhaler technique score and asthma control may reflect the multiple factors contributing to poor asthma control in the Jordanian population.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Inhalation
  • Adult
  • Anti-Asthmatic Agents / administration & dosage*
  • Asthma / diagnosis
  • Asthma / drug therapy*
  • Asthma / physiopathology
  • Checklist
  • Cross-Sectional Studies
  • Dry Powder Inhalers*
  • Equipment Design
  • Female
  • Humans
  • Jordan
  • Lung / drug effects*
  • Lung / physiopathology
  • Male
  • Metered Dose Inhalers*
  • Middle Aged
  • Prospective Studies
  • Surveys and Questionnaires
  • Task Performance and Analysis
  • Treatment Outcome

Substances

  • Anti-Asthmatic Agents

Associated data

  • ANZCTR/ACTRN12610000159055