J Clin Pathol. 1989 Mar;42(3):250-3.

Clinical importance of squamous metaplasia in invasive transitional cell carcinoma of the bladder.

Martin JE, Jenkins BJ, Zuk RJ, Blandy JP, Baithun SI.

Source

Department of Morbid Anatomy, London Hospital, London.

Abstract

One hundred cases of transitional cell carcinoma of the bladder were studied to determine whether squamous metaplasia and other histological features within the bladder can be of value in predicting outcome of treatment with radiotherapy. Sixty cases showed the changes of squamous metaplasia, and of this group 46 (78%) failed to respond to radiotherapy. A significant response rate of 90% was seen in the 40 tumours without squamous metaplasia. It is concluded that transitional cell carcinomas of the bladder showing squamous metaplasia are mainly resistant to radiotherapy and alternative treatment methods should be sought.

Comment in

J Clin Pathol. 1989 Nov;42(11):1227-8.

PMID:: 2703540; [PubMed - indexed for MEDLINE]
PMCID: PMC1141863

Free PMC Article

MeSH Terms

LinkOut - more resources

Full Text Sources

Medical

Bladder Cancer - MedlinePlus Health Information

Supplemental Content

Related citations

Prediction of response to radiotherapy in invasive bladder cancer. [Br J Urol. 1990]
Prediction of response to radiotherapy in invasive bladder cancer.
Jenkins BJ, Martin JE, Baithun SI, Zuk RJ, Oliver RT, Blandy JP. Br J Urol. 1990 Apr; 65(4):345-8.
Predicting the outcome of radical radiotherapy for invasive bladder cancer. [Eur Urol. 1993]
Predicting the outcome of radical radiotherapy for invasive bladder cancer.
Vale JA, A'Hern RP, Liu K, Hendry WF, Whitfield HN, Plowman PN, Sowter C, Slavin G. Eur Urol. 1993; 24(1):48-51.
Human chorionic gonadotrophin expression and histological findings as predictors of response to radiotherapy in carcinoma of the bladder. [Virchows Arch A Pathol Anat Histopathol. 19...]
Human chorionic gonadotrophin expression and histological findings as predictors of response to radiotherapy in carcinoma of the bladder.
Martin JE, Jenkins BJ, Zuk RJ, Oliver RT, Baithun SI. Virchows Arch A Pathol Anat Histopathol. 1989; 414(3):273-7.
Review Stromal osseous metaplasia in carcinoma of the bladder. [J Urol. 1991]
Review Stromal osseous metaplasia in carcinoma of the bladder.
Eble JN, Young RH. J Urol. 1991 Apr; 145(4):823-5.
Review Nested variant of transitional cell carcinoma with osseous metaplasia of the urinary bladder: a case report and review of published reports. [Int J Urol. 2007]
Review Nested variant of transitional cell carcinoma with osseous metaplasia of the urinary bladder: a case report and review of published reports.
Neşe N, Kandiloğlu AR, Atesçi YZ. Int J Urol. 2007 Apr; 14(4):365-7.

See reviews... See all...

Cited by 5 PubMed Central articles

Keratin 6 expression correlates to areas of squamous differentiation in multiple independent isolates of As(+3)-induced bladder cancer. [J Appl Toxicol. 2010]
Keratin 6 expression correlates to areas of squamous differentiation in multiple independent isolates of As(+3)-induced bladder cancer.
Cao L, Zhou XD, Sens MA, Garrett SH, Zheng Y, Dunlevy JR, Sens DA, Somji S. J Appl Toxicol. 2010 Jul; 30(5):416-30.
Histologic variants of urothelial bladder cancer and nonurothelial histology in bladder cancer. [Can Urol Assoc J. 2009]
Histologic variants of urothelial bladder cancer and nonurothelial histology in bladder cancer.
Chalasani V, Chin JL, Izawa JI. Can Urol Assoc J. 2009 Dec; 3(6 Suppl 4):S193-8.
Variation of keratin 7 expression and other phenotypic characteristics of independent isolates of cadmium transformed human urothelial cells (UROtsa). [Chem Res Toxicol. 2010]
Variation of keratin 7 expression and other phenotypic characteristics of independent isolates of cadmium transformed human urothelial cells (UROtsa).
Somji S, Zhou XD, Mehus A, Sens MA, Garrett SH, Lutz KL, Dunlevy JR, Zheng Y, Sens DA. Chem Res Toxicol. 2010 Feb 15; 23(2):348-56.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Clinical importance of squamous metaplasia in invasive transitional cell carcino...
Clinical importance of squamous metaplasia in invasive transitional cell carcinoma of the bladder.
J Clin Pathol. 1989 Mar ;42(3):250-3.

PubMed
Amantadine treatment is an independent predictor of improved survival in Parkins...
Amantadine treatment is an independent predictor of improved survival in Parkinson's disease.
Neurology. 1996 Jun ;46(6):1551-6.

PubMed
Clinical signs of TMJ osteoarthrosis and internal derangement 30 years after non...
Clinical signs of TMJ osteoarthrosis and internal derangement 30 years after nonsurgical treatment.
J Orofac Pain. 1994 Winter ;8(1):18-24.

PubMed
Investigation of normal flatus production in healthy volunteers.
Investigation of normal flatus production in healthy volunteers.
Gut. 1991 Jun ;32(6):665-9.

PubMed
Spinal bone loss and ovulatory disturbances.
Spinal bone loss and ovulatory disturbances.
N Engl J Med. 1990 Nov 1 ;323(18):1221-7.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

Clinical importance of squamous metaplasia in invasive transitional cell carcinoma of the bladder.

Source

Abstract

Comment in

MeSH Terms

MeSH Terms

LinkOut - more resources

Full Text Sources

Medical

Supplemental Content

Related citations

Cited by 5 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information