Abstract
Oxidative coupling using molybdenum(V) reagents provides fast access to highly functionalized 9-monosubstituted fluorenes. This synthetic approach is highly modular, is high yielding, and tolerates a variety of labile moieties, e.g. amides or iodo groups. The established protocol leads to promising precursors for pharmacologically important analogues of melatonin.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Combinatorial Chemistry Techniques
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Fluorenes / chemical synthesis*
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Fluorenes / chemistry
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Fluorenes / pharmacology
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Indicators and Reagents
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Melatonin / analogs & derivatives
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Melatonin / chemical synthesis
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Melatonin / chemistry
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Molecular Structure
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Molybdenum / chemistry*
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Oxidative Coupling
Substances
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Fluorenes
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Indicators and Reagents
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Molybdenum
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Melatonin