Data for the inhibition effects of recombinant lamprey CRBGP on the tube formation of HUVECs and new blood vessel generation in CAM models

Qi Jiang; Yu Liu; Meng Gou; Jianmei Han; Jihong Wang; Qingwei Li; Rong Xiao

doi:10.1016/j.dib.2016.01.004

Data for the inhibition effects of recombinant lamprey CRBGP on the tube formation of HUVECs and new blood vessel generation in CAM models

Data Brief. 2016 Jan 13:6:661-7. doi: 10.1016/j.dib.2016.01.004. eCollection 2016 Mar.

Authors

Qi Jiang¹, Yu Liu¹, Meng Gou¹, Jianmei Han¹, Jihong Wang¹, Qingwei Li¹, Rong Xiao¹

Affiliation

¹ School of Life Sciences, Liaoning Normal University, Dalian 116081, PR China; Lamprey Research Center, Liaoning Normal University, Dalian 116081, PR China.

Abstract

In the present data article, lamprey cysteine-rich buccal gland protein (CRBGP) which belongs to cysteine-rich secretory proteins (CRISPs) family was recombinant and expressed in Rosetta blue cells. After identification, the recombinant protein was purified through affinity chromatograph. The inhibition effects of recombinant lamprey CRBGP (rL-CRBGP) on tube formation of human umbilical vein endothelial cells (HUVECs) and new blood vessel generation in chick chorioallantoic membrane (CAM) models were analyzed. This paper contains data related to research concurrently published in "Anti-angiogenic activities of CRBGP from buccal glands of lampreys (Lampetra japonica)" [1].

Keywords: Anti-angiogenic activity; CRISP; Lamprey; rL-CRBGP.