Pregnancy outcome in pregnancies complicated with gestational diabetes mellitus and late preterm birth

Diabetes Res Clin Pract. 2016 Mar:113:198-203. doi: 10.1016/j.diabres.2015.12.018. Epub 2016 Jan 12.

Abstract

Aim: To assess pregnancy outcome among women with gestational diabetes mellitus (GDM) delivering at the late preterm period.

Methods: Retrospective observational cohort of all women with GDM who delivered a singleton fetus at the late preterm birth period (34+0/7 to 36+6/7 weeks of gestation). The study group included all women diagnosed with GDM and were compared to a control group of women delivering at the same gestational age period but without known GDM.

Results: 1849 women were included in the study, of whom 132 (7.1%) were diagnosed with GDM and 1717 (92.9%) were not. Women with GDM had a lower rate of spontaneous vaginal delivery (45.5% vs. 62.9%, p<0.001) and a higher rate of cesarean delivery (50.8% vs. 31.8%, p<0.001). GDM diagnosis incurs an adjusted ratio of 1.82 for cesarean delivery (95% CI 1.24-2.66, p=0.002). Neonates of mothers with GDM had significant higher mean birth weight and birth weight percentile, including higher rate of large-for-gestational age newborns. There were no differences in mortality or other parameters for neonatal morbidity.

Conclusion: according to our data, late preterm occurring in women with GDM does not confer an increased risk for neonatal complications.

Keywords: Gestational diabetes mellitus; Late; Neonatal Outcome; Preterm birth.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Birth Weight*
  • Cesarean Section / statistics & numerical data
  • Delivery, Obstetric
  • Diabetes, Gestational / epidemiology*
  • Female
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Israel / epidemiology
  • Male
  • Pregnancy
  • Pregnancy Outcome / epidemiology*
  • Premature Birth / epidemiology*
  • Retrospective Studies