Zika virus infection in a traveller returning from the Maldives, June 2015

Essi Marjana Korhonen; Eili Huhtamo; Teemu Smura; Hannimari Kallio-Kokko; Markku Raassina; Olli Vapalahti

doi:10.2807/1560-7917.ES.2016.21.2.30107

Zika virus infection in a traveller returning from the Maldives, June 2015

Euro Surveill. 2016;21(2). doi: 10.2807/1560-7917.ES.2016.21.2.30107.

Authors

Essi Marjana Korhonen¹, Eili Huhtamo, Teemu Smura, Hannimari Kallio-Kokko, Markku Raassina, Olli Vapalahti

Affiliation

¹ Department of Virology, Medicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.

PMID: 26794427
DOI: 10.2807/1560-7917.ES.2016.21.2.30107

Abstract

We report a Zika virus (ZIKV) infection in a patient with fever and rash after returning to Finland from Maldives, June 2015. The patient had dengue virus (DENV) IgG and IgM antibodies but pan-flavivirus RT-PCR and subsequent sequencing showed presence of ZIKV RNA in urine. Recent association of ZIKV with microcephaly highlights the need for laboratory differentiation of ZIKV from DENV infection and the circulation of ZIKV in areas outside its currently known distribution range.

Keywords: Zika virus; emerging infectious diseases; flavivirus; mosquito-borne; traveller.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Dengue / diagnosis*
Dengue Virus / isolation & purification
Exanthema / etiology
Fever / diagnosis
Fever / etiology
Fever / virology
Finland
Humans
Indian Ocean Islands
Male
Molecular Sequence Data
RNA, Viral / genetics
RNA, Viral / isolation & purification
Reverse Transcriptase Polymerase Chain Reaction
Sequence Analysis, RNA
Travel
Zika Virus / genetics
Zika Virus / isolation & purification*
Zika Virus Infection / diagnosis*
Zika Virus Infection / urine
Zika Virus Infection / virology

Substances

RNA, Viral