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Postepy Dermatol Alergol. 2015 Oct;32(5):331-6. doi: 10.5114/pdia.2015.54743. Epub 2015 Oct 29.

The association between smoking and the prevalence of metabolic syndrome and its components in patients with psoriasis aged 30 to 49 years.

Author information

  • 1Department of Dermatology, Municipal Hospital, Olsztyn, Poland. Head of the Department: Prof. Waldemar Placek MD, PhD.
  • 2Department of Dermatology, Venereology and Allergology, Gdansk Medical University, Gdansk, Poland. Head of the Department: Prof. Roman Nowicki MD, PhD.

Abstract

INTRODUCTION:

Cigarette smoking may exacerbate and cause psoriasis. Moreover, smokers are more likely to develop insulin resistance and metabolic syndrome (MS).

AIM:

To assess the prevalence of MS and its components in patients with psoriasis, who smoke, compared with the general Polish population of smokers.

MATERIAL AND METHODS:

We studied 29 patients with psoriasis (female = 9, male = 20), smokers, aged 30 to 49 years. Metabolic syndrome and its components were assessed using the IDF definition and compared to the results obtained in a representative sample of adult Poles in the NATPOL 2011 study in the same age group, including smokers.

RESULTS:

The results have shown that patients with psoriasis are more likely to be smokers (p < 0.0034) and the frequency of smoking in men is approximately 25% higher than in males of the control group (p < 0.0017). The prevalence of MS in patients with psoriasis who smoke was 27.58% and in the control group 25.2% (p > 0.05). Mean body mass index was 26.07 kg/m(2) in psoriasis patients and 25.59 kg/m(2) in the control group (p > 0.05), and abdominal obesity was 88.82 cm and 90.02 cm (p > 0.05), respectively. There were no differences in hypertension (34.48% vs. 31.6%, p < 0.05) and mean HOMA-IR (1.80 vs. 1.77, p > 0.05). In lipid parameters, the differences were observed only in women with psoriasis - higher levels of HDL, triglycerides and ApoB/ApoA1 index compared with addicted women in the control group.

CONCLUSIONS:

Men with psoriasis are more often addicted to smoking. Women with psoriasis who smoke have often disturbances of the lipid profile.

KEYWORDS:

insulin resistance; metabolic syndrome; psoriasis; smoking

PMID:
26759540
[PubMed]
PMCID:
PMC4692818
Free PMC Article
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