Curr Genet. 1989 Jun;15(6):457-9.

Cloning of the creA gene from Aspergillus nidulans: a gene involved in carbon catabolite repression.

Source

Department of Genetics, University of Adelaide, South Australia, Australia.

Abstract

The creA gene from A. nidulans has been cloned by complementation of a non-revertable mutant allele using a genomic library and marker rescue techniques. The rescued sequence was subcloned and a 2.3 kb fragment identified which complements several creA mutant alleles. Northern analyses showed that creA encodes a transcript of approximately 1.8 kb in length and that the levels of this transcript varied by up to two fold depending on the carbon source. Transformants containing more than two extra copies of creA grew as wildtype on a range of carbon sources, but there was evidence for tighter carbon catabolite repression.

PMID:: 2673558; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Full Text Sources

Supplemental Content

Related citations

Isolation of the facA (acetyl-coenzyme A synthetase) and acuE (malate synthase) genes of Aspergillus nidulans. [Mol Gen Genet. 1989]
Isolation of the facA (acetyl-coenzyme A synthetase) and acuE (malate synthase) genes of Aspergillus nidulans.
Sandeman RA, Hynes MJ. Mol Gen Genet. 1989 Jul; 218(1):87-92.
Analysis of the creA gene, a regulator of carbon catabolite repression in Aspergillus nidulans. [Mol Cell Biol. 1991]
Analysis of the creA gene, a regulator of carbon catabolite repression in Aspergillus nidulans.
Dowzer CE, Kelly JM. Mol Cell Biol. 1991 Nov; 11(11):5701-9.
Cloning and molecular characterisation of the amdR controlled gatA gene of Aspergillus nidulans. [Mol Gen Genet. 1989]
Cloning and molecular characterisation of the amdR controlled gatA gene of Aspergillus nidulans.
Richardson IB, Hurley SK, Hynes MJ. Mol Gen Genet. 1989 May; 217(1):118-25.
Review Ethanol catabolism in Aspergillus nidulans: a model system for studying gene regulation. [Prog Nucleic Acid Res Mol Biol. 2001]
Review Ethanol catabolism in Aspergillus nidulans: a model system for studying gene regulation.
Felenbok B, Flipphi M, Nikolaev I. Prog Nucleic Acid Res Mol Biol. 2001; 69:149-204.
Review Fungal catabolic gene regulation: molecular genetic analysis of the amdS gene of Aspergillus nidulans. [Genetica. 1993]
Review Fungal catabolic gene regulation: molecular genetic analysis of the amdS gene of Aspergillus nidulans.
Davis MA, Kelly JM, Hynes MJ. Genetica. 1993; 90(2-3):133-45.

See reviews... See all...

Cited by 8 PubMed Central articles

Genetic modification of carbon catabolite repression in Trichoderma reesei for improved protein production. [Appl Environ Microbiol. 2009]
Genetic modification of carbon catabolite repression in Trichoderma reesei for improved protein production.
Nakari-Setälä T, Paloheimo M, Kallio J, Vehmaanperä J, Penttilä M, Saloheimo M. Appl Environ Microbiol. 2009 Jul; 75(14):4853-60. Epub 2009 May 15.
Molecular characterization and analysis of the acrB gene of Aspergillus nidulans: a gene identified by genetic interaction as a component of the regulatory network that includes the CreB deubiquitination enzyme. [Genetics. 2003]
Molecular characterization and analysis of the acrB gene of Aspergillus nidulans: a gene identified by genetic interaction as a component of the regulatory network that includes the CreB deubiquitination enzyme.
Boase NA, Lockington RA, Adams JR, Rodbourn L, Kelly JM. Genetics. 2003 May; 164(1):95-104.
The wide-domain carbon catabolite repressor CreA indirectly controls expression of the Aspergillus nidulans xlnB gene, encoding the acidic endo-beta-(1,4)-xylanase X(24). [J Bacteriol. 2001]
The wide-domain carbon catabolite repressor CreA indirectly controls expression of the Aspergillus nidulans xlnB gene, encoding the acidic endo-beta-(1,4)-xylanase X(24).
Orejas M, MacCabe AP, Pérez-González JA, Kumar S, Ramón D. J Bacteriol. 2001 Mar; 183(5):1517-23.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Cloning of the creA gene from Aspergillus nidulans: a gene involved in carbon ca...
Cloning of the creA gene from Aspergillus nidulans: a gene involved in carbon catabolite repression.
Curr Genet. 1989 Jun ;15(6):457-9.

PubMed
Biomechanical evaluation of longitudinal arch stability.
Biomechanical evaluation of longitudinal arch stability.
Foot Ankle. 1993 Jul-Aug ;14(6):353-7.

PubMed
Late-term abortion.
Late-term abortion.
JAMA. 1998 Aug 26 ;280(8):724-9.

PubMed
Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins.
Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins.
J Biol Chem. 1999 Jan 1 ;274(1):7-10.

PubMed
Effects of altered glucokinase gene copy number on blood glucose homoeostasis.
Effects of altered glucokinase gene copy number on blood glucose homoeostasis.
Biochem Soc Trans. 1997 Feb ;25(1):113-7.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to:

Cloning of the creA gene from Aspergillus nidulans: a gene involved in carbon catabolite repression.

Source

Abstract

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Supplemental Content

Related citations

Cited by 8 PubMed Central articles

Related information

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information