The antiretroviral and cytostatic activity, and metabolism of 3'-azido-2',3'-dideoxythymidine, 3'-fluoro-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly cell type-dependent. [Adv Exp Med Biol. 1989]
The antiretroviral and cytostatic activity, and metabolism of 3'-azido-2',3'-dideoxythymidine, 3'-fluoro-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly cell type-dependent.
Balzarini J, Matthes E, Meeus P, Johns DG, De Clercq E. Adv Exp Med Biol. 1989; 253B:407-13.
Review Clinical applications of 3'-azido-2',3'-dideoxythymidine (AZT) and related dideoxynucleosides. [Med Res Rev. 1990]
Review Clinical applications of 3'-azido-2',3'-dideoxythymidine (AZT) and related dideoxynucleosides.
Broder S. Med Res Rev. 1990 Oct-Dec; 10(4):419-39.
[Suppression of the human immunodeficiency virus in cultured cells by 5'-phosphites of 3'-azido-2',3'-dideoxynucleosides]. [Mol Biol (Mosk). 1990]
[Suppression of the human immunodeficiency virus in cultured cells by 5'-phosphites of 3'-azido-2',3'-dideoxynucleosides].
Karamov EV, Lukashov VV, Tarusova NB, Kornilaeva GV, Rodova MA, Kukhanova MK, Kraevskiĭ AA. Mol Biol (Mosk). 1990 Nov-Dec; 24(6):1695-701.
[Inhibition of HIV reproduction in cell culture by 5'-phosphonates of 3'-azido-2',3'-dideoxynucleosides]. [Mol Biol (Mosk). 1989]
[Inhibition of HIV reproduction in cell culture by 5'-phosphonates of 3'-azido-2',3'-dideoxynucleosides].
Tarusova NB, Khorlin AA, Kraevskiĭ AA, Korneeva MN, Nosik DN, Kruglov IV, Galegov GA, Bibilashvili RSh. Mol Biol (Mosk). 1989 Nov-Dec; 23(6):1716-24.
Review HIV drug resistance. [AIDS Res Hum Retroviruses. 1992]
Review HIV drug resistance.
Richman DD. AIDS Res Hum Retroviruses. 1992 Jun; 8(6):1065-71.

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