Rare diseases and orphan drugs: 500 years ago

Orphanet J Rare Dis. 2015 Dec 21:10:161. doi: 10.1186/s13023-015-0353-3.

Abstract

In 1581 Rembert Dodoens wrote "Medicinalium observationum exempla rara, recognita et aucta" a Latin book about the diagnosis and treatment of disorders with a low prevalence.

Publication types

  • Biography
  • Historical Article
  • Letter

MeSH terms

  • Belgium
  • History, 16th Century
  • Humans
  • Orphan Drug Production / history*
  • Rare Diseases / history*

Personal name as subject

  • Rembertus Dodonaeus