Trends Genet. 1989 May;5(5):139-43.

The great GATC: DNA methylation in E. coli.

Abstract

In Escherichia coli the methylation of the adenine in the sequence 5'-GATC-3' is catalysed by the dam gene product, a DNA adenine methylase. We review the proposed roles for this methylation, and the sequence it modifies, in mismatch repair, DNA-protein interaction, gene expression, the initiation of chromosome replication, chromosome segregation, chromosome structure and the occurrence of mutational hotspots.

PMID:: 2667217; [PubMed - indexed for MEDLINE]

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The Escherichia coli chromosome contains specific, unmethylated dam and dcm sites. [Proc Natl Acad Sci U S A. 1992]
The Escherichia coli chromosome contains specific, unmethylated dam and dcm sites.
Ringquist S, Smith CL. Proc Natl Acad Sci U S A. 1992 May 15; 89(10):4539-43.
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