Medical Treatments of Hidradenitis Suppurativa: More Options, Less Evidence

Dermatol Clin. 2016 Jan;34(1):91-6. doi: 10.1016/j.det.2015.08.006.

Abstract

Hidradenitis suppurativa is a common debilitating skin disease that has been neglected by science. The disease is getting more and more attention, reflected by the rising number of scientific publications. There is a clear need for effective treatment. We are still at the beginning of improving care for these patients as demonstrated by the low levels of evidence for the medical treatments. Many of these therapies showed promising results, but are still waiting to be validated in randomized, controlled trials. Much more research is needed to strengthen the Level of Evidence for these therapies and thus improve patient care.

Keywords: Acne inversa; Evidence; Hidradenitis suppurativa; Treatment.

Publication types

  • Review

MeSH terms

  • Acitretin / therapeutic use
  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Infective Agents / therapeutic use
  • Cyclosporine / therapeutic use
  • Dapsone / therapeutic use
  • Dermatologic Agents / therapeutic use
  • Gluconates / therapeutic use
  • Hidradenitis Suppurativa / drug therapy*
  • Hormones / therapeutic use
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Injections, Intralesional
  • Keratolytic Agents / therapeutic use
  • Metformin / therapeutic use
  • Ustekinumab / therapeutic use

Substances

  • Adrenal Cortex Hormones
  • Anti-Infective Agents
  • Dermatologic Agents
  • Gluconates
  • Hormones
  • Hypoglycemic Agents
  • Keratolytic Agents
  • Cyclosporine
  • Dapsone
  • Metformin
  • Ustekinumab
  • Acitretin
  • gluconic acid