Response to comment on "Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2"

Lawrence Steinman; S Sohail Ahmed

doi:10.1126/scitranslmed.aad6789

Response to comment on "Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2"

Sci Transl Med. 2015 Nov 18;7(314):314lr2. doi: 10.1126/scitranslmed.aad6789.

Authors

Lawrence Steinman¹, S Sohail Ahmed²

Affiliations

¹ Neurology and Neuroscience, Stanford University School of Medicine, Stanford, CA 94305, USA. steinman@stanford.edu sohail.q.ahmed@gsk.com.
² Global Clinical Sciences, Novartis Vaccines Srl, Siena 53100, Italy. steinman@stanford.edu sohail.q.ahmed@gsk.com.

PMID: 26582897
DOI: 10.1126/scitranslmed.aad6789

Abstract

Vassalli et al.'s study does not involve or provide additional data regarding influenza virus, influenza vaccines, human samples, animal models of narcolepsy, or experiments related to mimicry and cross-reactivity. They present data on the distribution of hypocretin (HCRT) (also known as orexin) receptors in the brain of an engineered mouse developed by them.

Publication types

Letter
Comment

MeSH terms

Antibodies, Viral / immunology*
Cross Reactions / immunology*
Humans
Orexin Receptors / immunology*
RNA-Binding Proteins / immunology*
Viral Core Proteins / immunology*

Substances

Antibodies, Viral
Orexin Receptors
RNA-Binding Proteins
Viral Core Proteins