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Enzymatic catalysis in anhydrous organic solvents.
Not only do enzymes work vigorously in anhydrous organic media, but in this unnatural milieu they acquire remarkable properties such as greatly enhanced stability, radically altered substrate and enantiomeric specificities, molecular memory, and the ability to catalyse unusual reactions.
PMID: 2658221 [PubMed - indexed for MEDLINE]
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Cited by 11 PubMed Central articles
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Analysis of metabolic pathways by the growth of cells in the presence of organic solvents.
Spinnler HE, Ginies C, Khan JA, Vulfson EN.
Proc Natl Acad Sci U S A. 1996 Apr 16; 93(8):3373-6.
[Proc Natl Acad Sci U S A. 1996]
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Crystal structure of triosephosphate isomerase from Trypanosoma cruzi in hexane.
Gao XG, Maldonado E, Pérez-Montfort R, Garza-Ramos G, de Gómez-Puyou MT, Gómez-Puyou A, Rodríguez-Romero A.
Proc Natl Acad Sci U S A. 1999 Aug 31; 96(18):10062-7.
[Proc Natl Acad Sci U S A. 1999]
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Water: foldase activity in catalyzing polypeptide conformational rearrangements.
Xu F, Cross TA.
Proc Natl Acad Sci U S A. 1999 Aug 3; 96(16):9057-61.
[Proc Natl Acad Sci U S A. 1999]
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