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J Antimicrob Chemother. 1989 Apr;23 Suppl D:105-8.

Comparison of single-dose cefmetazole and cefotetan prophylaxis in women undergoing primary caesarean section.

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  • 1Department of Microbiology, University of Iowa College of Medicine, Iowa City.


The efficacies of a single 2 g intra-operative iv dose of cefmetazole or cefotetan in women undergoing non-elective Caesarean section were compared. Thirty-six women (18 in each group) completed the double-blind protocol. Both antibiotics were equally effective as agents for prophylaxis of post-Caesarean infections. Combined data suggest that routine multi-dose antibiotic prophylaxis regimens could be replaced by a single dose regimen.

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