Complement Inflamm. 1989;6(2):104-11.

Mechanisms of tissue damage by the membrane attack complex of complement.

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Department of Medical Biochemistry, University of Wales College of Medicine, Cardiff, UK.

Abstract

This article explores the role of the cytolytic membrane attack complex of complement in the pathogenesis of inflammatory diseases. Evidence of nucleated cell resistance to lysis by the membrane attack complex and the stimulation of secretion of pro-inflammatory factors in the absence of cell death in a variety of cell types in vitro are documented, and the possible significance of these non-lethal effects to the pathogenesis of inflammatory diseases highlighted.

PMID:: 2656078; [PubMed - indexed for MEDLINE]

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Mechanisms of tissue damage by the membrane attack complex of complement.

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Abstract

Publication Types, MeSH Terms, Substances

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Supplemental Content

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Cited by 8 PubMed Central articles

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