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J Am Dent Assoc. 1989 Mar;118(3):276, 278, 280.

Safety of amide local anesthetics in patients susceptible to malignant hyperthermia.

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  • 1Harvard Medical School, Boston, MA 02114.


Earlier reports on malignant hyperthermia warned against the use of local anesthetics in the amide class in persons susceptible to the syndrome. The preponderance of data supports the safety of amide local anesthetics in such patients, and these agents should not be withheld from persons at risk for developing the syndrome.

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