Review and Updates in Regenerative and Personalized Medicine, Preclinical Animal Models, and Clinical Care in Cardiovascular Medicine

J Cardiovasc Transl Res. 2015 Nov;8(8):466-74. doi: 10.1007/s12265-015-9657-x. Epub 2015 Oct 9.

Abstract

The goal of this paper is to provide an updated review for scientists and clinicians on the major areas in cardiovascular medicine published in the Journal. Leading topics in regenerative and personalized medicine are presented along with a critical overview of the field. New standards in large preclinical animal models of pulmonary hypertension and left bundle branch block are highlighted. Finally, clinical care in the areas of atherosclerosis, the aortic valve, platelet biology, and myocarditis is discussed as well as autonomic modulation therapies.

Keywords: Autonomic modulation; Cardiovascular; Electronic health record; Genomics; Heart; Left bundle branch block; Myocarditis; Personalized medicine; Platelets; Preclinical; Pulmonary hypertension; Regenerative medicine; Stem cell.

Publication types

  • Review

MeSH terms

  • Animals
  • Cardiology / trends*
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / genetics
  • Cardiovascular Diseases / physiopathology
  • Cardiovascular Diseases / therapy*
  • Diffusion of Innovation
  • Disease Models, Animal*
  • Humans
  • Precision Medicine / trends*
  • Regenerative Medicine / trends*