Metastatic Ocular Melanoma Presenting as a Heart-Compressing Mediastinal Mass

Ann Thorac Surg. 2015 Oct;100(4):1448-50. doi: 10.1016/j.athoracsur.2014.12.055.

Abstract

Ocular malignant melanoma is characterized by an unpredictable course, and metastases may develop, after a long disease-free interval, anywhere in the body. The mediastinum, however, is a rare site of these metastases, and metastatic melanoma presenting as a large mediastinal mass is quite unusual. We report herein a peculiar case of a solitary, late metastasis of malignant ocular melanoma, manifesting as a sizable posterior mediastinal mass and presenting with paroxysmal atrial fibrillation. Transthoracic echocardiography, computed tomography scan findings, and surgical treatment and pathologic examination are described.

Publication types

  • Case Reports

MeSH terms

  • Cardiac Tamponade / etiology*
  • Eye Neoplasms / pathology*
  • Humans
  • Male
  • Mediastinal Neoplasms / complications*
  • Mediastinal Neoplasms / secondary*
  • Melanoma / complications*
  • Melanoma / secondary*
  • Middle Aged