Nocturnal hypoxia and functional outcome in stroke patients

NeuroRehabilitation. 2015;36(3):339-43. doi: 10.3233/NRE-151222.

Abstract

Background: Sleep disorders and nocturnal hypoxia are common in patients with cerebrovascular disease. Sleep-disordered breathing is associated with a poor functional outcome in stroke patients.

Objective: We investigated the relationship between nocturnal hypoxia and functional outcome in the rehabilitation phase of stroke patients.

Methods: Thirty patients with stroke and 20 controls were included. Functional status was evaluated with the Functional Independence Measure (FIM). Pulse oximetry was performed overnight from 21.00 h to 07.00 h. Baseline awake oxygen saturation, nocturnal oxygen saturation, the lowest nocturnal oxygen saturation, and the >4% Oxygen Desaturation Index (ODI) were calculated.

Results: The mean oxygen saturation measurements were not significantly different among the groups (p > 0.05). There was no significant relationship between the FIM scores and the oxygen saturation measurements of the stroke patients (p > 0.05). The baseline oxygen saturation in patients with disease duration of 3 months or less was 94.67, and it was 96.56 (p = 0.016) in those with disease duration of more than 3 months.

Conclusion: This study showed that nocturnal oxygen saturation was not associated with functional outcome in therehabilitation phase of stroke patients.

Keywords: Nocturnal hypoxia; functional outcome; oxygen saturation; stroke.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Female
  • Humans
  • Hypoxia / diagnosis*
  • Hypoxia / metabolism
  • Hypoxia / rehabilitation
  • Male
  • Middle Aged
  • Oximetry / methods
  • Recovery of Function* / physiology
  • Sleep Apnea Syndromes / diagnosis*
  • Sleep Apnea Syndromes / metabolism
  • Sleep Apnea Syndromes / rehabilitation
  • Stroke / diagnosis*
  • Stroke / metabolism
  • Stroke Rehabilitation
  • Treatment Outcome
  • Wakefulness / physiology