Gene-based meta-analysis of genome-wide association studies implicates new loci involved in obesity

Affiliations

• ¹ Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden, Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, SE-751 41 Uppsala, Sweden.
• ² Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA, Analytical and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
• ³ Laboratory of Experimental Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands.
• ⁴ Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA, Estonian Genome Center, University of Tartu, Tartu 51010, Estonia.
• ⁵ Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA, Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark, Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.
• ⁶ Center for Statistical Genetics, Department of Biostatistics.
• ⁷ Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
• ⁸ Department of Epidemiology.
• ⁹ Department of Internal Medicine, Division of Gastroenterology, Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.
• ¹⁰ Laboratory of Experimental Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht 3584 CX, The Netherlands, Laboratory of Clinical Chemistry and Hematology, Division Laboratories & Pharmacy, UMC Utrecht, Utrecht, The Netherlands.
• ¹¹ St George's, University of London, London SW17 0RE, UK.
• ¹² Department of Epidemiology, Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
• ¹³ MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, UK, The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA, The Genetics of Obesity and Related Metabolic Traits Program, The Mindich Child Health and Development Institute.
• ¹⁴ Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA 02115, USA, Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.
• ¹⁵ Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
• ¹⁶ Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, SE-751 41 Uppsala, Sweden, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK and Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA erik.ingelsson@medsci.uu.se.