[SH3BP2 heterozygous mutation amplifies macrophage inflammatory responses to infection in a mouse model of cherubism]

Med Sci (Paris). 2015 Jun-Jul;31(6-7):589-91. doi: 10.1051/medsci/20153106005. Epub 2015 Jul 7.

[Article in French]

Authors

Marcel Deckert¹, Virginie Prod'Homme¹

Affiliation

¹ Centre méditerranéen de médecine moléculaire (C3M), Inserm, U1065, équipe microenvironnement, signalisation et cancer, bâtiment universitaire ARCHIMED, 151, route Saint Antoine de Ginestière, 06204 Nice Cedex 03, France - Université de Nice Sophia Antipolis, faculté de médecine, laboratoire d'excellence Signalife, 06103 Nice, France.

PMID: 26152156
DOI: 10.1051/medsci/20153106005

No abstract available

Publication types

News

MeSH terms

Adaptor Proteins, Signal Transducing / genetics*
Animals
Cherubism / genetics*
Cherubism / immunology
Cherubism / pathology*
Disease Models, Animal
Heterozygote
Infections / genetics
Infections / immunology*
Infections / pathology
Inflammation / genetics*
Inflammation / pathology
Macrophages / immunology*
Mice
Mice, Knockout
Mutation, Missense

Substances

Adaptor Proteins, Signal Transducing
Sh3bp2 protein, mouse