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Clin Exp Rheumatol. 1989 Sep-Oct;7(5):521-3.

Altered lymphocyte proliferation by low dosage laser irradiation.

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  • 1Department of Orthopaedic Surgery, Shiga University of Medical Science, Otsu, Japan.


The effect of gallium-aluminum-arsenide laser irradiation on the proliferation of human lymphocytes in culture in response to mitogenic stimulation by phytohemagglutinin was investigated. Mitogenic proliferation was inhibited by the laser irradiation at a low energy fluence and enhanced at a high energy fluence. The results indicate that low-watt laser irradiation can interfere with the immune response in vitro, and similar interference could occur in patients with rheumatoid arthritis subjected to laser therapy, if an appropriate dosage is chosen.

[PubMed - indexed for MEDLINE]
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