Sjögren's syndrome: association with type-1 diabetes mellitus

Br J Rheumatol. 1989 Dec;28(6):518-20. doi: 10.1093/rheumatology/28.6.518.

Abstract

This study of 102 unselected type-1 diabetic patients has shown that sicca symptoms affect 55% of the patients, although sometimes only during hyperglycaemic phases. While these symptoms might be attributable to the diabetes, the frequency of antinuclear antibodies in those suspected of having Sjögren's (25% by HEp-2) and particularly anti-Ro antibodies (32% by ELISA) reinforces the suspicion that Sjögren's syndrome may underlie their presence.

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Antinuclear / analysis
  • Diabetes Mellitus, Type 1 / complications*
  • Female
  • Humans
  • Hyperglycemia
  • Male
  • Middle Aged
  • Prevalence
  • Sjogren's Syndrome / complications*
  • Sjogren's Syndrome / diagnosis
  • Sjogren's Syndrome / epidemiology

Substances

  • Antibodies, Antinuclear