Retrospective evaluation of ProcalAmine administration in a population of hospitalized ICU dogs: 36 cases (2010-2013)

J Vet Emerg Crit Care (San Antonio). 2015 May-Jun;25(3):405-12. doi: 10.1111/vec.12306. Epub 2015 Apr 21.

Abstract

Objective: To describe the use of ProcalAmine as a source of parenteral nutrition in hospitalized dogs and to report complications possibly referable to its use.

Design: Retrospective study.

Settings: Private veterinary teaching hospital.

Animals: Thirty-six dogs hospitalized in ICU receiving ProcalAmine between October 2010 and March 2013.

Interventions: None.

Measurements and main results: The most common underlying disease process in this population of dogs was trauma (n = 8). Median duration of administration was 4 days and median resting energy requirement provided via ProcalAmine was 33%. ProcalAmine was administered via central catheters in 86% of cases and via peripheral catheters in 14% of cases. The overall mechanical complication rate was 19%. Metabolic complications possibly associated with ProcalAmine administration were documented in 12/36 dogs. Hyponatremia was most commonly identified (n = 6) followed by hyperglycemia (n = 4), hypochloremia (n = 2), azotemia (n = 2), metabolic alkalosis (n = 2), hyperchloremia (n = 1), and metabolic acidosis (n = 1).

Conclusion: ProcalAmine appears to be relatively safe and a viable option for parenteral nutrition in ill and injured dogs. Due to the potential for electrolyte derangements and other metabolic complications, daily monitoring of these parameters is advisable.

Keywords: PPN; TPN; amino acids; parenteral nutrition; protein.

Publication types

  • Evaluation Study

MeSH terms

  • Amino Acids / administration & dosage
  • Amino Acids / adverse effects
  • Amino Acids / therapeutic use*
  • Animals
  • Catheterization / veterinary
  • Critical Care
  • Deglutition Disorders / therapy
  • Deglutition Disorders / veterinary*
  • Dog Diseases / therapy*
  • Dogs
  • Electrolytes / administration & dosage
  • Electrolytes / adverse effects
  • Electrolytes / therapeutic use*
  • Female
  • Glycerol / administration & dosage
  • Glycerol / adverse effects
  • Glycerol / therapeutic use*
  • Intensive Care Units
  • Male
  • Parenteral Nutrition Solutions / administration & dosage
  • Parenteral Nutrition Solutions / adverse effects
  • Parenteral Nutrition Solutions / therapeutic use*
  • Retrospective Studies
  • Veterinary Medicine

Substances

  • Amino Acids
  • Electrolytes
  • Parenteral Nutrition Solutions
  • ProcalAmine
  • Glycerol