Treatment time, ease of use and cost associated with use of Equashield™, PhaSeal® , or no closed system transfer device for administration of cancer chemotherapy to a dog model

K Kicenuik; N Northrup; A Dawson; J Locke; J A Villamil; J Chretin; G Sfiligoi; C Clifford; M Rosenberg; T Hamilton; R Regan; M Parsons-Doherty; C Mallett; J Philibert; J Impellizeri; E Hofmeister

doi:10.1111/vco.12148

Treatment time, ease of use and cost associated with use of Equashield™, PhaSeal^® , or no closed system transfer device for administration of cancer chemotherapy to a dog model

Vet Comp Oncol. 2017 Mar;15(1):163-173. doi: 10.1111/vco.12148. Epub 2015 Apr 10.

Authors

K Kicenuik¹, N Northrup¹, A Dawson¹, J Locke², J A Villamil³, J Chretin⁴, G Sfiligoi⁵, C Clifford⁶, M Rosenberg⁷, T Hamilton⁸, R Regan⁸, M Parsons-Doherty⁹, C Mallett¹⁰, J Philibert¹¹, J Impellizeri¹², E Hofmeister¹

Affiliations

¹ Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA.
² Southeast Veterinary Oncology, Orange Park, FL, USA.
³ Animal Cancer Care Clinic, Ft. Lauderdale, FL, USA.
⁴ VCA West Los Angeles Animal Hospital, Los Angeles, CA, USA.
⁵ Wheat Ridge Animal Hospital, Wheat Ridge, CO, USA.
⁶ Hope Veterinary Specialists, Malvern, PA, USA.
⁷ Veterinary Cancer Group, Woodland Hills, CA, USA.
⁸ BluePearl Georgia Veterinary Specialists, Sandy Springs, GA, USA.
⁹ Department of Small Animal Medicine and Surgery, University of Guelph Ontario Veterinary College, Guelph, Ontario, Canada.
¹⁰ Columbia River Veterinary Specialists, Vancouver, WA, USA.
¹¹ Portland Veterinary Specialists, Portland, ME, USA.
¹² Veterinary Oncology Services, NY, Middletown, NY, USA.

PMID: 25864458
DOI: 10.1111/vco.12148

Abstract

This prospective experimental simulation study evaluated the efficiency, ease of use (EOU) and cost of administering chemotherapy with two closed system transfer devices (CSTD, Equashield™ and PhaSeal^® ) and no CSTD. Forty-six veterinary technicians (VT) working in oncology specialty practices were timed during chemotherapy administration simulated with water and a model canine limb 10 times with each system and with no CSTD. EOU and likelihood of recommending each system were rated by VT using visual analog scales. Costs were obtained from veterinary distributors. Administration was fastest with Equashield™ (P = 0.0003), but the difference was not enough to affect case flow. Equashield™ was easier to use than PhaSeal^® or no CSTD (P = 0.002), however VT recommended both CSTD more strongly than no CSTD (P < 0.0001). Equashield™ cost less than PhaSeal^® but was sold only in bulk quantities. CSTD did not decrease efficiency in administering chemotherapy and were readily accepted by VT.

Keywords: ONB; antineoplastic drug; device; occupational safety.

Publication types

Comparative Study

MeSH terms

Analysis of Variance
Animal Technicians / psychology
Animals
Antineoplastic Agents / administration & dosage*
Attitude
Dog Diseases / drug therapy*
Dogs
Equipment Design / methods*
Equipment Design / psychology
Georgia
Humans
Neoplasms / drug therapy
Neoplasms / veterinary*
Occupational Exposure / prevention & control*
Protective Devices
Safety Management / methods*
Syringes
Time
Visual Analog Scale

Substances

Antineoplastic Agents