Diagnostic Errors in a PICU: Insights From the Morbidity and Mortality Conference

Pediatr Crit Care Med. 2015 Jun;16(5):468-76. doi: 10.1097/PCC.0000000000000398.

Abstract

Objectives: To describe diagnostic errors identified among patients discussed at a PICU morbidity and mortality conference in terms of Goldman classification, medical category, severity, preventability, contributing factors, and occurrence in the diagnostic process.

Design: Retrospective record review of morbidity and mortality conference agendas, patient charts, and autopsy reports.

Setting: Single tertiary referral PICU in Baltimore, MD.

Patients: Ninety-six patients discussed at the PICU morbidity and mortality conference from November 2011 to December 2012.

Interventions: None.

Measurements and main results: Eighty-nine of 96 patients (93%) discussed at the PICU morbidity and mortality conference had at least one identified safety event. A total of 377 safety events were identified. Twenty patients (21%) had identified misdiagnoses, comprising 5.3% of all safety events. Out of 20 total diagnostic errors identified, 35% were discovered at autopsy while 55% were reported primarily through the morbidity and mortality conference. Almost all diagnostic errors (95%) could have had an impact on patient survival or safety. Forty percent of errors did not cause actual patient harm, but 25% were severe enough to have potentially contributed to death (40% no harm vs 35% some harm vs 25% possibly contributed to death). Half of the diagnostic errors (50%) were rated as preventable. There were slightly more system-related factors (40%) solely contributing to diagnostic errors compared with cognitive factors (20%); however, 35% had both system and cognitive factors playing a role. Most errors involved vascular (35%) followed by neurologic (30%) events.

Conclusions: Diagnostic errors in the PICU are not uncommon and potentially cause patient harm. Most appear to be preventable by targeting both cognitive- and system-related contributing factors. Prospective studies are needed to further determine how and why diagnostic errors occur in the PICU and what interventions would likely be effective for prevention.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Diagnostic Errors / classification
  • Diagnostic Errors / mortality
  • Diagnostic Errors / prevention & control
  • Diagnostic Errors / statistics & numerical data*
  • Female
  • Humans
  • Infant
  • Intensive Care Units, Pediatric / statistics & numerical data*
  • Male
  • Morbidity
  • Retrospective Studies
  • Severity of Illness Index
  • Tertiary Care Centers