Syndrome in question. Immunoglobulin light chain amyloidosis

An Bras Dermatol. 2015 Mar-Apr;90(2):270-1. doi: 10.1590/abd1806-4841.20153320.

Abstract

Immunoglobulin light chain amyloidosis is the most common acquired systemic amyloidosis. Its presentation is often insidious and progressive, which may delay diagnosis. The authors describe a rare case of immunoglobulin light chain amyloidosis in a 34-year-old man with scleroderma-like manifestation substantiated by multifarious laboratory investigations and the histopathologic feature of involved skin lesions stained with Congo red and crystal violet. This helps to maintain a high clinical suspicion of the disease when confronting similar skin presentation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amyloidosis / immunology
  • Amyloidosis / pathology*
  • Biopsy
  • Flow Cytometry
  • Humans
  • Immunoglobulin Light Chains*
  • Male
  • Skin / pathology
  • Skin Diseases / immunology
  • Skin Diseases / pathology*
  • Syndrome

Substances

  • Immunoglobulin Light Chains