Determinants of Activity Levels in African Americans With Mild Cognitive Impairment

Alzheimer Dis Assoc Disord. 2016 Jan-Mar;30(1):41-6. doi: 10.1097/WAD.0000000000000096.

Abstract

Engaging in cognitive, social, and physical activities may prevent cognitive decline. In a sample of older African Americans with mild cognitive impairment (MCI; N=221), we investigated the cross-sectional relationships between activity levels and participants' demographic, clinical, and neuropsychological characteristics. The average age of participants was 75.4 years (SD, 7.0); 177 (80.1%) were women. Participation in cognitive/social activities was positively associated with education, depression, literacy, mobility, instrumental activities of daily living (IADL), verbal learning, and subcomponents of executive function. A linear regression identified IADLs, education, depression, and verbal learning as independent predictors. Participation in physical activities was positively associated with sex, depression, IADLs, and subcomponents of executive function. An ordinal regression identified executive function and depression as independent correlates. These data suggest that unique characteristics are associated with cognitive/social and physical activities in older African Americans with MCI. These characteristics, coupled with low activity levels, may increase the risk of progression from MCI to dementia. Culturally relevant behavioral interventions to reduce cognitive decline in this high-risk population are needed.

Trial registration: ClinicalTrials.gov NCT01299766.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Activities of Daily Living* / psychology
  • Aged
  • Aged, 80 and over
  • Black or African American / statistics & numerical data*
  • Cognitive Dysfunction / ethnology*
  • Cognitive Dysfunction / physiopathology
  • Cognitive Dysfunction / psychology
  • Cross-Sectional Studies
  • Depression
  • Disease Progression
  • Executive Function / physiology
  • Female
  • Humans
  • Interpersonal Relations*
  • Male
  • Neuropsychological Tests / statistics & numerical data

Associated data

  • ClinicalTrials.gov/NCT01299766