Error related negativity and multi-source interference task in children with attention deficit hyperactivity disorder-combined type

Arq Neuropsiquiatr. 2015 Mar;73(3):223-6. doi: 10.1590/0004-282X20140227.

Abstract

Objective: To compare performance of children with attention deficit hyperactivity disorders-combined (ADHD-C) type with control children in multi-source interference task (MSIT) evaluated by means of error related negativity (ERN).

Method: We studied 12 children with ADHD-C type with a median age of 7 years, control children were age- and gender-matched. Children performed MSIT and simultaneous recording of ERN.

Results: We found no differences in MSIT parameters among groups. We found no differences in ERN variables between groups. We found a significant association of ERN amplitude with MSIT in children with ADHD-C type. Some correlation went in positive direction (frequency of hits and MSIT amplitude), and others in negative direction (frequency of errors and RT in MSIT).

Conclusion: Children with ADHD-C type exhibited a significant association between ERN amplitude with MSIT. These results underline participation of a cingulo-fronto-parietal network and could help in the comprehension of pathophysiological mechanisms of ADHD.

MeSH terms

  • Attention Deficit Disorder with Hyperactivity / physiopathology*
  • Case-Control Studies
  • Cerebral Cortex / physiopathology
  • Child
  • Electroencephalography
  • Evoked Potentials / physiology*
  • Female
  • Humans
  • Male
  • Neuropsychological Tests
  • Reaction Time / physiology
  • Task Performance and Analysis*
  • Time Factors