Older people living in nursing homes in Denmark are among the most frail. The mean age at moving in is 84 years. Mean time living in nursing homes is 25 months for men and 32 for women. The dwellers can choose their usual general practitioner but change in organisation is now being evaluated. Medical focus is dementia, prevention of delirium, falls and especially the medical treatment. Polypharmacy is a huge challenge. Collaboration and communication with nursing staff is essential in order to do prevention, rehabilitation and palliation among the frail dwellers.