Your browser version may not work well with NCBI's Web applications. More information here...
1: Hillside J Clin Psychiatry. 1989;11(2):107-19.Links

Treatment of neuroleptic-induced akathisia with propranolol: a controlled replication study.

Kramer MS, Gorkin R, DiJohnson C.

Coatesville Veterans Administration Medical Center, Pa.

Twelve DSM-IIIR diagnosed schizophrenics, with neuroleptic-induced akathisia (NIA), were treated with either propranolol or matched placebo for two days, followed by a treatment crossover phase for five more days. Raters and patients were "blind" to treatment. This study shows that 120 mg of propranolol a day is more effective than placebo in reducing akathisia, and that propranolol's antiakathisic effect may require several days of treatment.

PMID: 2577308 [PubMed - indexed for MEDLINE]

Patient Drug Information