Hum Genet. 1989 Oct;83(3):297-9.

Assignment of the gene(s) involved in the expression of the proliferation-related Ki-67 antigen to human chromosome 10.

Schonk DM, Kuijpers HJ, van Drunen E, van Dalen CH, Geurts van Kessel AH, Verheijen R, Ramaekers FC.

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Department of Human Genetics, University Hospital of Nijmegen, The Netherlands.

Abstract

The antigen recognized by the monoclonal antibody Ki-67 is a proliferation-related nucleolus-associated constituent used as a marker for cycling cells in tumor diagnosis. Antibody Ki-67 reacts with human proliferating cells, but not with hamster and mouse cells. Expression of the Ki-67 antigen was studied in a panel of human-rodent somatic cell hybrids. The results indicate that a gene involved in the expression of the antigen is located on chromosome 10.

PMID:: 2571566; [PubMed - indexed for MEDLINE]

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Cited by 4 PubMed Central articles

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Hum Genet. 1989 Oct ;83(3):297-9.

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