Induction of labor by oral prostaglandin E2 in protracted pregnancy

Int J Gynaecol Obstet. 1989 Aug;29(4):325-8. doi: 10.1016/0020-7292(89)90357-3.

Abstract

Induction of labor was performed in 20 pregnant females with postmaturity (greater than 294 days) using either oral PGE2 tablets (0.5 mg) or i.v. oxytocin drip (each group n = 10). The induction-establishment interval was significantly shorter in the oxytocin group (P less than 0.005). Moreover, the uterine activity (in Alexandria units) at 3 h post-induction and at the end of the first stage of labor, was significantly higher with i.v. oxytocin (P less than 0.005). However, the induction-delivery interval did not differ in both groups. All cases delivered spontaneously with a satisfactory Apgar score.

Publication types

  • Comparative Study

MeSH terms

  • Administration, Oral
  • Adult
  • Dinoprostone / administration & dosage*
  • Dinoprostone / adverse effects
  • Female
  • Fetal Monitoring
  • Heart Rate, Fetal / drug effects
  • Humans
  • Infusions, Intravenous
  • Labor, Induced / methods*
  • Oxytocin / administration & dosage
  • Oxytocin / adverse effects
  • Pregnancy
  • Pregnancy, Prolonged / drug effects*
  • Uterine Contraction / drug effects

Substances

  • Oxytocin
  • Dinoprostone