J Med Genet. 1989 May;26(5):294-8.

Fertility in a male with trisomy 21.

Sheridan R, Llerena J Jr, Matkins S, Debenham P, Cawood A, Bobrow M.

Division of Medical and Molecular Genetics, United Medical School, Guy's Hospital, London.

Comment in:

J Med Genet. 1992 Feb;29(2):141.

We review the published reports on reproduction in cases of non-mosaic trisomy 21 (Down's syndrome) and present the first fully documented case of a non-mosaic male with Down's syndrome fathering a pregnancy, a fact which has important implications in the light of caring for these people in the community.

PMID: 2567354 [PubMed - indexed for MEDLINE]

PMCID: PMC1015594

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Paternal trisomy 21 mosaicism and Down's syndrome.
Am J Hum Genet. 1971 Nov; 23(6):592-601.

[Am J Hum Genet. 1971]
Recurrent Down's syndrome due to maternal ovarian trisomy 21 mosaicism.
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[Arch Gynecol Obstet. 1994]
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[J Med Genet. 1994]
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[Cancer. 1987]
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[Cancer Genet Cytogenet. 1987]
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Cited by 4 PubMed Central articles

Genetic issues in the care of the adolescent patient.
Velsher L. Paediatr Child Health. 2003 Jan; 8(1):36-9.

[Paediatr Child Health. 2003]
Non-obstructive azoospermia and maturation arrest with complex translocation 46,XY t(9;13;14)(p22;q21.2;p13) is consistent with the Luciani-Guo hypothesis of latent aberrant autosomal regions and infertility.
Sills ES, Kim JJ, Witt MA, Palermo GD. Cell Chromosome. 2005 Sep 14; 4:2. Epub 2005 Sep 14.

[Cell Chromosome. 2005]
Down syndrome in association with features of the androgen insensitivity syndrome.
Viner RM, Shimura N, Brown BD, Green AJ, Hughes IA. J Med Genet. 1996 Jul; 33(7):574-7.

[J Med Genet. 1996]
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